PLA2G12B FISH Probe
The PLA2G12B FISH probe is designed to hybridize to the PLA2G12B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PLA2G12B-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
PLA2G12B-20-RE | 20 (40 μL) | 200 μL | ||
PLA2G12B-20-GO | 20 (40 μL) | 200 μL | ||
PLA2G12B-20-GR | 20 (40 μL) | 200 μL | ||
PLA2G12B-20-AQ | 20 (40 μL) | 200 μL | ||
PLA2G12B-20-DIG | 20 (40 μL) | 200 μL | ||
PLA2G12B-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene belongs to the phospholipase A2 (PLA2) group of enzymes, which function in glycolipid hydrolysis with the release of free fatty acids and lysophospholipids. This family member has altered phospholipid-binding properties and is catalytically inactive. The protein is secreted, and together with microsomal triglyceride transfer protein, it functions to regulate HNF4alpha-induced hepatitis C virus infectivity. The expression of this gene is down-regulated in various tumors, suggesting that it may function as a negative regulator of tumor progression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: PLA2G12B
Gene Name: Phospholipase A2 Group XIIB
Chromosome: CHR10: 74694937-74714510
Locus: 10q22.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: PLA2G12B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLA2G12B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping