PKR FISH Probe
The PKR FISH probe is designed to hybridize to the PKR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PKLR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PKLR-20-RE | 20 (40 μL) | 200 μL |  |
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| PKLR-20-GO | 20 (40 μL) | 200 μL |  |
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| PKLR-20-GR | 20 (40 μL) | 200 μL |  |
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| PKLR-20-AQ | 20 (40 μL) | 200 μL |  |
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| PKLR-20-DIG | 20 (40 μL) | 200 μL |  |
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| PKLR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PKLR
Gene Name: Pyruvate Kinase L/R
Chromosome: CHR1: 155259083-155271225
Locus: 1q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PKR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PKLR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping