PKM Break Apart FISH Probe
Empire Genomics’ PKM Break Apart FISH Probe is designed to flank the PKM gene and is typically used for detecting PKM rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PKMBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| PKMBA-20-AQOR | 20 (40 μL) | 200 μL |
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| PKMBA-20-GOGR | 20 (40 μL) | 200 μL |
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| PKMBA-20-GORE | 20 (40 μL) | 200 μL |
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| PKMBA-20-GRGO | 20 (40 μL) | 200 μL |
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| PKMBA-20-GRRE | 20 (40 μL) | 200 μL |
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| PKMBA-20-ORGR | 20 (40 μL) | 200 μL |
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| PKMBA-20-REGO | 20 (40 μL) | 200 μL |
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| PKMBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
Gene Details
Gene Symbol: PKM
Gene Name: Pyruvate Kinase M1/2
Chromosome: CHR15: 72231623-72199028
Locus: 15q23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PKM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PKM-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping