PKM FISH Probe
The PKM FISH probe is designed to hybridize to the PKM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PKM-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PKM-20-RE | 20 (40 μL) | 200 μL |  |
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| PKM-20-GO | 20 (40 μL) | 200 μL |  |
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| PKM-20-GR | 20 (40 μL) | 200 μL |  |
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| PKM-20-AQ | 20 (40 μL) | 200 μL |  |
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| PKM-20-DIG | 20 (40 μL) | 200 μL |  |
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| PKM-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
Gene Details
Gene Symbol: PKM
Gene Name: Pyruvate Kinase M1/2
Chromosome: CHR15: 72231623-72199028
Locus: 15q23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PKM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PKM-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping