PKC FISH Probe
The PKC FISH probe is designed to hybridize to the PKC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRKCG-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRKCG-20-RE | 20 (40 μL) | 200 μL |  |
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| PRKCG-20-GO | 20 (40 μL) | 200 μL |  |
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| PRKCG-20-GR | 20 (40 μL) | 200 μL |  |
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| PRKCG-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRKCG-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRKCG-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: PRKCG
Gene Name: Protein Kinase C Gamma
Chromosome: CHR19: 54385466-54410901
Locus: 19q13.42
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PKC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRKCG-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping