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PITX3 Break Apart FISH Probe

Empire Genomics’ PITX3 Break Apart FISH Probe is designed to flank the PITX3 gene and is typically used for detecting PITX3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
PITX3BA-20-GROR  (Standard Design) 20 (40 μL) 200 μL
PITX3BA-20-AQOR 20 (40 μL) 200 μL
PITX3BA-20-GOGR 20 (40 μL) 200 μL
PITX3BA-20-GORE 20 (40 μL) 200 μL
PITX3BA-20-GRGO 20 (40 μL) 200 μL
PITX3BA-20-GRRE 20 (40 μL) 200 μL
PITX3BA-20-ORGR 20 (40 μL) 200 μL
PITX3BA-20-REGO 20 (40 μL) 200 μL
PITX3BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: PITX3

Gene Name: Paired Like Homeodomain 3

Chromosome: CHR10: 103989945-104001231

Locus: 10q24.32

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Genomic Fusions in Pigmented Spindle Cell Nevus of Reed

Pigmented spindle cell nevus (PSCN) of Reed is a type of Spitz nevus that can be difficult to diagnose. It is thought that gene fusions could be the basis of PSCN. The molecular characteristics of PSCN was under study with the use of RNA-sequencing and FISH. FISH analysis was performed with our MERTK and PITX3 fusion probes among other FISH tests. It was found that the majority of PSCN of Reed cases are the result of gene fusions, with the most frequent fusion involving NTRK3.
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Product Details

Product: PITX3 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PITX3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping