PITX2 FISH Probe
The PITX2 FISH probe is designed to hybridize to the PITX2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PITX2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PITX2-20-RE | 20 (40 μL) | 200 μL |  |
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| PITX2-20-GO | 20 (40 μL) | 200 μL |  |
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| PITX2-20-GR | 20 (40 μL) | 200 μL |  |
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| PITX2-20-AQ | 20 (40 μL) | 200 μL |  |
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| PITX2-20-DIG | 20 (40 μL) | 200 μL |  |
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| PITX2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PITX2
Gene Name: Paired Like Homeodomain 2
Chromosome: CHR4: 111538579-111563279
Locus: 4q25
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PITX2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PITX2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping