PIN1 Break Apart FISH Probe
Empire Genomics’ PIN1 Break Apart FISH Probe is designed to flank the PIN1 gene and is typically used for detecting PIN1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PIN1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PIN1BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PIN1BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PIN1BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PIN1BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PIN1BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PIN1BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PIN1BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PIN1BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
Gene Details
Gene Symbol: PIN1
Gene Name: Peptidylprolyl Cis/trans Isomerase, NIMA-interacting 1
Chromosome: CHR19: 9945882-9960365
Locus: 19p13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PIN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PIN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping