PIM1 Break Apart FISH Probe
Empire Genomics’ PIM1 Break Apart FISH Probe is designed to flank the PIM1 gene and is typically used for detecting PIM1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PIM1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
PIM1BA-20-AQOR | 20 (40 μL) | 200 μL | ||
PIM1BA-20-GOGR | 20 (40 μL) | 200 μL | ||
PIM1BA-20-GORE | 20 (40 μL) | 200 μL | ||
PIM1BA-20-GRGO | 20 (40 μL) | 200 μL | ||
PIM1BA-20-GROR | 20 (40 μL) | 200 μL | ||
PIM1BA-20-GRRE | 20 (40 μL) | 200 μL | ||
PIM1BA-20-REGO | 20 (40 μL) | 200 μL | ||
PIM1BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: PIM1
Gene Name: Pim-1 Proto-oncogene, Serine/threonine Kinase
Chromosome: CHR6: 37137921-37143204
Locus: 6p21.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: PIM1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PIM1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping