PIM1 FISH Probe
The PIM1 FISH probe is designed to hybridize to the PIM1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PIM1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PIM1-20-RE | 20 (40 μL) | 200 μL |  |
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| PIM1-20-GO | 20 (40 μL) | 200 μL |  |
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| PIM1-20-GR | 20 (40 μL) | 200 μL |  |
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| PIM1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PIM1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PIM1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: PIM1
Gene Name: Pim-1 Proto-oncogene, Serine/threonine Kinase
Chromosome: CHR6: 37137921-37143204
Locus: 6p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PIM1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PIM1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping