PIK3R5 Break Apart FISH Probe
Empire Genomics’ PIK3R5 Break Apart FISH Probe is designed to flank the PIK3R5 gene and is typically used for detecting PIK3R5 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PIK3R5BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
PIK3R5BA-20-AQOR | 20 (40 μL) | 200 μL | ||
PIK3R5BA-20-GOGR | 20 (40 μL) | 200 μL | ||
PIK3R5BA-20-GORE | 20 (40 μL) | 200 μL | ||
PIK3R5BA-20-GRGO | 20 (40 μL) | 200 μL | ||
PIK3R5BA-20-GRRE | 20 (40 μL) | 200 μL | ||
PIK3R5BA-20-ORGR | 20 (40 μL) | 200 μL | ||
PIK3R5BA-20-REGO | 20 (40 μL) | 200 μL | ||
PIK3R5BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011]
Gene Details
Gene Symbol: PIK3R5
Gene Name: Phosphoinositide-3-kinase Regulatory Subunit 5
Chromosome: CHR17: 8782232-8869024
Locus: 17p13.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: PIK3R5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PIK3R5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping