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PIK3CD Break Apart FISH Probe

Empire Genomics’ PIK3CD Break Apart FISH Probe is designed to flank the PIK3CD gene and is typically used for detecting PIK3CD rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
PIK3CDBA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PIK3CDBA-20-AQOR 20 (40 μL) 200 μL
PIK3CDBA-20-GOGR 20 (40 μL) 200 μL
PIK3CDBA-20-GORE 20 (40 μL) 200 μL
PIK3CDBA-20-GRGO 20 (40 μL) 200 μL
PIK3CDBA-20-GROR 20 (40 μL) 200 μL
PIK3CDBA-20-GRRE 20 (40 μL) 200 μL
PIK3CDBA-20-REGO 20 (40 μL) 200 μL
PIK3CDBA-20-REGR 20 (40 μL) 200 μL

Gene Summary

Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010]

Gene Details

Gene Symbol: PIK3CD

Gene Name: Phosphatidylinositol-4,5-bisphosphate 3-kinase Catalytic Subunit Delta

Chromosome: CHR1: 9711789-9789172

Locus: 1p36.22

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

High-throughput Sequencing of Subcutaneous Panniculitis-like T-Cell Lymphoma Reveals Candidate Pathogenic Mutations

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare cancer that’s challenging to distinguish from lupus panniculitis (LP). Few studies have been conducted on the genetic and molecular development of the disease. This team performed whole-exome sequencing on 4 SPTCLs and 1 systemic T-cell lymphoma, along with 2 cases of LP. They also used targeted sequencing to analyze 41 genes (with known implications across hematolyhpoid malignancies) on 5 additional SPTCL biopsies. Empire Genomics’ PDCD1 and PIK3CD FISH probes were used to detect copy number variants in the 2 genes, which are abnormalities associated with lymphoma but not LP.
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Product Details

Product: PIK3CD FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PIK3CD-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping