PIK3C2A Break Apart FISH Probe
Empire Genomics’ PIK3C2A Break Apart FISH Probe is designed to flank the PIK3C2A gene and is typically used for detecting PIK3C2A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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PIK3C2ABA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
PIK3C2ABA-20-AQOR | 20 (40 μL) | 200 μL | ||
PIK3C2ABA-20-GOGR | 20 (40 μL) | 200 μL | ||
PIK3C2ABA-20-GORE | 20 (40 μL) | 200 μL | ||
PIK3C2ABA-20-GRGO | 20 (40 μL) | 200 μL | ||
PIK3C2ABA-20-GRRE | 20 (40 μL) | 200 μL | ||
PIK3C2ABA-20-ORGR | 20 (40 μL) | 200 μL | ||
PIK3C2ABA-20-REGO | 20 (40 μL) | 200 μL | ||
PIK3C2ABA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PIK3C2A
Gene Name: Phosphatidylinositol-4-phosphate 3-kinase Catalytic Subunit Type 2 Alpha
Chromosome: CHR11: 17108123-17191354
Locus: 11p15.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PIK3C2A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PIK3C2A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping