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PICALM FISH Probe

The PICALM FISH probe is designed to hybridize to the PICALM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
PICALM-20-OR  (Standard Design) 20 (40 μL) 200 μL
PICALM-20-RE 20 (40 μL) 200 μL
PICALM-20-GO 20 (40 μL) 200 μL
PICALM-20-GR 20 (40 μL) 200 μL
PICALM-20-AQ 20 (40 μL) 200 μL
PICALM-20-DIG 20 (40 μL) 200 μL
PICALM-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

Gene Details

Gene Symbol: PICALM

Gene Name: Phosphatidylinositol Binding Clathrin Assembly Protein

Chromosome: CHR11: 85668213-85780923

Locus: 11q14.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: PICALM FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PICALM-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping