PICALM FISH Probe
The PICALM FISH probe is designed to hybridize to the PICALM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PICALM-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PICALM-20-RE | 20 (40 μL) | 200 μL |  |
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| PICALM-20-GO | 20 (40 μL) | 200 μL |  |
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| PICALM-20-GR | 20 (40 μL) | 200 μL |  |
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| PICALM-20-AQ | 20 (40 μL) | 200 μL |  |
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| PICALM-20-DIG | 20 (40 μL) | 200 μL |  |
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| PICALM-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Gene Details
Gene Symbol: PICALM
Gene Name: Phosphatidylinositol Binding Clathrin Assembly Protein
Chromosome: CHR11: 85668213-85780923
Locus: 11q14.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PICALM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PICALM-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping