PHOX2B Break Apart FISH Probe
Empire Genomics’ PHOX2B Break Apart FISH Probe is designed to flank the PHOX2B gene and is typically used for detecting PHOX2B rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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PHOX2BBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
PHOX2BBA-20-AQOR | 20 (40 μL) | 200 μL | ||
PHOX2BBA-20-GOGR | 20 (40 μL) | 200 μL | ||
PHOX2BBA-20-GORE | 20 (40 μL) | 200 μL | ||
PHOX2BBA-20-GRGO | 20 (40 μL) | 200 μL | ||
PHOX2BBA-20-GRRE | 20 (40 μL) | 200 μL | ||
PHOX2BBA-20-ORGR | 20 (40 μL) | 200 μL | ||
PHOX2BBA-20-REGO | 20 (40 μL) | 200 μL | ||
PHOX2BBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016]
Gene Details
Gene Symbol: PHOX2B
Gene Name: Paired Like Homeobox 2b
Chromosome: CHR4: 41746098-41750987
Locus: 4p13
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PHOX2B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PHOX2B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping