PHOX2B FISH Probe
The PHOX2B FISH probe is designed to hybridize to the PHOX2B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PHOX2B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| PHOX2B-20-RE | 20 (40 μL) | 200 μL |  |
|
| PHOX2B-20-GO | 20 (40 μL) | 200 μL |  |
|
| PHOX2B-20-GR | 20 (40 μL) | 200 μL |  |
|
| PHOX2B-20-AQ | 20 (40 μL) | 200 μL |  |
|
| PHOX2B-20-DIG | 20 (40 μL) | 200 μL |  |
|
| PHOX2B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016]
Gene Details
Gene Symbol: PHOX2B
Gene Name: Paired Like Homeobox 2b
Chromosome: CHR4: 41746098-41750987
Locus: 4p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PHOX2B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PHOX2B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping