PHKA2 Break Apart FISH Probe
Empire Genomics’ PHKA2 Break Apart FISH Probe is designed to flank the PHKA2 gene and is typically used for detecting PHKA2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHKA2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHKA2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PHKA2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PHKA2BA-20-GORE | 20 (40 μL) | 200 μL |
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| PHKA2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PHKA2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PHKA2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| PHKA2BA-20-REGO | 20 (40 μL) | 200 μL |
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| PHKA2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A, also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported, but the full-length nature of these variants has not been determined.[provided by RefSeq, Feb 2010]
Gene Details
Gene Symbol: PHKA2
Gene Name: Phosphorylase Kinase Regulatory Subunit Alpha 2
Chromosome: CHRX: 18910415-19002480
Locus: Xp22.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PHKA2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PHKA2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping