PHGDH FISH Probe
The PHGDH FISH probe is designed to hybridize to the PHGDH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PHGDH-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
PHGDH-20-RE | 20 (40 μL) | 200 μL | ||
PHGDH-20-GO | 20 (40 μL) | 200 μL | ||
PHGDH-20-GR | 20 (40 μL) | 200 μL | ||
PHGDH-20-AQ | 20 (40 μL) | 200 μL | ||
PHGDH-20-DIG | 20 (40 μL) | 200 μL | ||
PHGDH-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: PHGDH
Gene Name: Phosphoglycerate Dehydrogenase
Chromosome: CHR1: 120254418-120286849
Locus: 1p12
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PHGDH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PHGDH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping