PGPEP1 FISH Probe
The PGPEP1 FISH probe is designed to hybridize to the PGPEP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PGPEP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PGPEP1-20-RE | 20 (40 μL) | 200 μL |  |
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| PGPEP1-20-GO | 20 (40 μL) | 200 μL |  |
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| PGPEP1-20-GR | 20 (40 μL) | 200 μL |  |
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| PGPEP1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PGPEP1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PGPEP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The gene encodes a cysteine protease and member of the peptidase C15 family of proteins. The encoded protein cleaves amino terminal pyroglutamate residues from protein substrates including thyrotropin-releasing hormone and other neuropeptides. Expression of this gene may be downregulated in colorectal cancer, while activity of the encoded protein may be negatively correlated with cancer progression in colorectal cancer patients. Activity of the encoded protease may also be altered in other disease states including in liver cirrhosis, which is associated with reduced protease activity, and in necrozoospermia, which is associated with elevated protease activity. [provided by RefSeq, Jul 2016]
Gene Details
Gene Symbol: PGPEP1
Gene Name: Pyroglutamyl-peptidase I
Chromosome: CHR19: 18451407-18480763
Locus: 19p13.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PGPEP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PGPEP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping