PGK1 FISH Probe
The PGK1 FISH probe is designed to hybridize to the PGK1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PGK1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PGK1-20-RE | 20 (40 μL) | 200 μL |  |
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| PGK1-20-GO | 20 (40 μL) | 200 μL |  |
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| PGK1-20-GR | 20 (40 μL) | 200 μL |  |
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| PGK1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PGK1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PGK1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
Gene Details
Gene Symbol: PGK1
Gene Name: Phosphoglycerate Kinase 1
Chromosome: CHRX: 77359665-77382324
Locus: Xq21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PGK1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PGK1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping