PGIS FISH Probe
The PGIS FISH probe is designed to hybridize to the PGIS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTGIS-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PTGIS-20-RE | 20 (40 μL) | 200 μL |  |
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| PTGIS-20-GO | 20 (40 μL) | 200 μL |  |
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| PTGIS-20-GR | 20 (40 μL) | 200 μL |  |
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| PTGIS-20-AQ | 20 (40 μL) | 200 μL |  |
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| PTGIS-20-DIG | 20 (40 μL) | 200 μL |  |
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| PTGIS-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PTGIS
Gene Name: Prostaglandin I2 Synthase
Chromosome: CHR20: 48120410-48184707
Locus: 20q13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PGIS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTGIS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping