PFKFB2 Break Apart FISH Probe
Empire Genomics’ PFKFB2 Break Apart FISH Probe is designed to flank the PFKFB2 gene and is typically used for detecting PFKFB2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PFKFB2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PFKFB2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PFKFB2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PFKFB2BA-20-GORE | 20 (40 μL) | 200 μL |
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| PFKFB2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PFKFB2BA-20-GROR | 20 (40 μL) | 200 μL |
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| PFKFB2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PFKFB2BA-20-REGO | 20 (40 μL) | 200 μL |
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| PFKFB2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PFKFB2
Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Chromosome: CHR1: 207226619-207254368
Locus: 1q32.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PFKFB2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PFKFB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping