PFKFB1 FISH Probe
The PFKFB1 FISH probe is designed to hybridize to the PFKFB1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PFKFB1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PFKFB1-20-RE | 20 (40 μL) | 200 μL |  |
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| PFKFB1-20-GO | 20 (40 μL) | 200 μL |  |
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| PFKFB1-20-GR | 20 (40 μL) | 200 μL |  |
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| PFKFB1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PFKFB1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PFKFB1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]
Gene Details
Gene Symbol: PFKFB1
Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Chromosome: CHRX: 54959589-55020511
Locus: Xp11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PFKFB1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PFKFB1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping