PEX5 Break Apart FISH Probe
Empire Genomics’ PEX5 Break Apart FISH Probe is designed to flank the PEX5 gene and is typically used for detecting PEX5 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PEX5BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PEX5BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PEX5BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PEX5BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PEX5BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PEX5BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PEX5BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PEX5BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PEX5BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
Gene Details
Gene Symbol: PEX5
Gene Name: Peroxisomal Biogenesis Factor 5
Chromosome: CHR12: 7341758-7371169
Locus: 12p13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PEX5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PEX5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping