PDK3 FISH Probe
The PDK3 FISH probe is designed to hybridize to the PDK3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDK3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PDK3-20-RE | 20 (40 μL) | 200 μL |  |
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| PDK3-20-GO | 20 (40 μL) | 200 μL |  |
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| PDK3-20-GR | 20 (40 μL) | 200 μL |  |
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| PDK3-20-AQ | 20 (40 μL) | 200 μL |  |
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| PDK3-20-DIG | 20 (40 μL) | 200 μL |  |
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| PDK3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Gene Details
Gene Symbol: PDK3
Gene Name: Pyruvate Dehydrogenase Kinase 3
Chromosome: CHRX: 24483343-24568583
Locus: Xp22.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PDK3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PDK3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping