PDHA1 Break Apart FISH Probe
Empire Genomics’ PDHA1 Break Apart FISH Probe is designed to flank the PDHA1 gene and is typically used for detecting PDHA1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PDHA1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
PDHA1BA-20-AQOR | 20 (40 μL) | 200 μL | ||
PDHA1BA-20-GOGR | 20 (40 μL) | 200 μL | ||
PDHA1BA-20-GORE | 20 (40 μL) | 200 μL | ||
PDHA1BA-20-GRGO | 20 (40 μL) | 200 μL | ||
PDHA1BA-20-GROR | 20 (40 μL) | 200 μL | ||
PDHA1BA-20-GRRE | 20 (40 μL) | 200 μL | ||
PDHA1BA-20-REGO | 20 (40 μL) | 200 μL | ||
PDHA1BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
Gene Details
Gene Symbol: PDHA1
Gene Name: Pyruvate Dehydrogenase E1 Alpha 1 Subunit
Chromosome: CHRX: 19362010-19379825
Locus: Xp22.12
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PDHA1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PDHA1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping