PDGFRB FISH Probe
The PDGFRB FISH probe is designed to hybridize to the PDGFRB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDGFRB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PDGFRB-20-RE | 20 (40 μL) | 200 μL |  |
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| PDGFRB-20-GO | 20 (40 μL) | 200 μL |  |
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| PDGFRB-20-GR | 20 (40 μL) | 200 μL |  |
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| PDGFRB-20-AQ | 20 (40 μL) | 200 μL |  |
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| PDGFRB-20-DIG | 20 (40 μL) | 200 μL |  |
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| PDGFRB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: PDGFRB
Gene Name: Platelet Derived Growth Factor Receptor Beta
Chromosome: CHR5: 149493401-149535422
Locus: 5q32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PDGFRB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PDGFRB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping