PDGFB Break Apart FISH Probe
Empire Genomics’ PDGFB Break Apart FISH Probe is designed to flank the PDGFB gene and is typically used for detecting PDGFB rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDGFBBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PDGFBBA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PDGFBBA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PDGFBBA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PDGFBBA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PDGFBBA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PDGFBBA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| PDGFBBA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PDGFBBA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: PDGFB
Gene Name: Platelet Derived Growth Factor Subunit B
Chromosome: CHR22: 39619684-39640957
Locus: 22q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PDGFB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PDGFB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping