PDE6B Break Apart FISH Probe
Empire Genomics’ PDE6B Break Apart FISH Probe is designed to flank the PDE6B gene and is typically used for detecting PDE6B rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDE6BBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDE6BBA-20-AQOR | 20 (40 μL) | 200 μL |
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| PDE6BBA-20-GOGR | 20 (40 μL) | 200 μL |
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| PDE6BBA-20-GORE | 20 (40 μL) | 200 μL |
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| PDE6BBA-20-GRGO | 20 (40 μL) | 200 μL |
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| PDE6BBA-20-GROR | 20 (40 μL) | 200 μL |
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| PDE6BBA-20-GRRE | 20 (40 μL) | 200 μL |
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| PDE6BBA-20-REGO | 20 (40 μL) | 200 μL |
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| PDE6BBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Gene Details
Gene Symbol: PDE6B
Gene Name: Phosphodiesterase 6B
Chromosome: CHR4: 619362-664681
Locus: 4p16.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PDE6B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PDE6B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping