PDE6A FISH Probe
The PDE6A FISH probe is designed to hybridize to the PDE6A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDE6A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| PDE6A-20-RE | 20 (40 μL) | 200 μL |  |
|
| PDE6A-20-GO | 20 (40 μL) | 200 μL |  |
|
| PDE6A-20-GR | 20 (40 μL) | 200 μL |  |
|
| PDE6A-20-AQ | 20 (40 μL) | 200 μL |  |
|
| PDE6A-20-DIG | 20 (40 μL) | 200 μL |  |
|
| PDE6A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PDE6A
Gene Name: Phosphodiesterase 6A
Chromosome: CHR5: 149237518-149324356
Locus: 5q32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PDE6A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PDE6A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping