PCMT1 FISH Probe
The PCMT1 FISH probe is designed to hybridize to the PCMT1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PCMT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PCMT1-20-RE | 20 (40 μL) | 200 μL |  |
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| PCMT1-20-GO | 20 (40 μL) | 200 μL |  |
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| PCMT1-20-GR | 20 (40 μL) | 200 μL |  |
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| PCMT1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PCMT1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PCMT1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Gene Details
Gene Symbol: PCMT1
Gene Name: Protein-L-isoaspartate (D-aspartate) O-methyltransferase
Chromosome: CHR6: 150070830-150132557
Locus: 6q25.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PCMT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PCMT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping