PCDHA12 Break Apart FISH Probe
Empire Genomics’ PCDHA12 Break Apart FISH Probe is designed to flank the PCDHA12 gene and is typically used for detecting PCDHA12 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PCDHA12BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PCDHA12BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PCDHA12BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PCDHA12BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PCDHA12BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PCDHA12BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PCDHA12BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PCDHA12BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PCDHA12BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PCDHA12
Gene Name: Protocadherin Alpha 12
Chromosome: CHR5: 140254930-140391929
Locus: 5q31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PCDHA12 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PCDHA12-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping