PCDH-ALPHA8 FISH Probe
The PCDH-ALPHA8 FISH probe is designed to hybridize to the PCDH-ALPHA8 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PCDHA8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PCDHA8-20-RE | 20 (40 μL) | 200 μL |  |
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| PCDHA8-20-GO | 20 (40 μL) | 200 μL |  |
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| PCDHA8-20-GR | 20 (40 μL) | 200 μL |  |
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| PCDHA8-20-AQ | 20 (40 μL) | 200 μL |  |
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| PCDHA8-20-DIG | 20 (40 μL) | 200 μL |  |
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| PCDHA8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PCDHA8
Gene Name: Protocadherin Alpha 8
Chromosome: CHR5: 140220906-140391929
Locus: 5q31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PCDH-ALPHA8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PCDHA8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping