PCBP1 Break Apart FISH Probe
Empire Genomics’ PCBP1 Break Apart FISH Probe is designed to flank the PCBP1 gene and is typically used for detecting PCBP1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PCBP1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PCBP1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PCBP1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PCBP1BA-20-GORE | 20 (40 μL) | 200 μL |
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| PCBP1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PCBP1BA-20-GROR | 20 (40 μL) | 200 μL |
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| PCBP1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PCBP1BA-20-REGO | 20 (40 μL) | 200 μL |
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| PCBP1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PCBP1
Gene Name: Poly(rC) Binding Protein 1
Chromosome: CHR2: 70314584-70316334
Locus: 2p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PCBP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PCBP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping