PBX1 Break Apart FISH Probe
Empire Genomics’ PBX1 Break Apart FISH Probe is designed to flank the PBX1 gene and is typically used for detecting PBX1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PBX1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PBX1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PBX1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PBX1BA-20-GORE | 20 (40 μL) | 200 μL |
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| PBX1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PBX1BA-20-GROR | 20 (40 μL) | 200 μL |
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| PBX1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PBX1BA-20-REGO | 20 (40 μL) | 200 μL |
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| PBX1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
Gene Details
Gene Symbol: PBX1
Gene Name: PBX Homeobox 1
Chromosome: CHR1: 164528596-164821060
Locus: 1q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PBX1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PBX1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping