PARN FISH Probe
The PARN FISH probe is designed to hybridize to the PARN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PARN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PARN-20-RE | 20 (40 μL) | 200 μL |  |
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| PARN-20-GO | 20 (40 μL) | 200 μL |  |
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| PARN-20-GR | 20 (40 μL) | 200 μL |  |
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| PARN-20-AQ | 20 (40 μL) | 200 μL |  |
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| PARN-20-DIG | 20 (40 μL) | 200 μL |  |
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| PARN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Details
Gene Symbol: PARN
Gene Name: Poly(A)-specific Ribonuclease
Chromosome: CHR16: 14529556-14724128
Locus: 16p13.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PARN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PARN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping