PANK2 FISH Probe
The PANK2 FISH probe is designed to hybridize to the PANK2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PANK2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PANK2-20-RE | 20 (40 μL) | 200 μL |  |
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| PANK2-20-GO | 20 (40 μL) | 200 μL |  |
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| PANK2-20-GR | 20 (40 μL) | 200 μL |  |
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| PANK2-20-AQ | 20 (40 μL) | 200 μL |  |
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| PANK2-20-DIG | 20 (40 μL) | 200 μL |  |
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| PANK2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PANK2
Gene Name: Pantothenate Kinase 2
Chromosome: CHR20: 3869485-3904502
Locus: 20p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PANK2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PANK2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping