PAM FISH Probe
The PAM FISH probe is designed to hybridize to the PAM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PAM-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| PAM-20-RE | 20 (40 μL) | 200 μL |  |
|
| PAM-20-GO | 20 (40 μL) | 200 μL |  |
|
| PAM-20-GR | 20 (40 μL) | 200 μL |  |
|
| PAM-20-AQ | 20 (40 μL) | 200 μL |  |
|
| PAM-20-DIG | 20 (40 μL) | 200 μL |  |
|
| PAM-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: PAM
Gene Name: Peptidylglycine Alpha-amidating Monooxygenase
Chromosome: CHR5: 102201526-102366808
Locus: 5q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PAM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PAM-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping