PAK5 FISH Probe
The PAK5 FISH probe is designed to hybridize to the PAK5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PAK5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PAK5-20-RE | 20 (40 μL) | 200 μL |  |
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| PAK5-20-GO | 20 (40 μL) | 200 μL |  |
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| PAK5-20-GR | 20 (40 μL) | 200 μL |  |
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| PAK5-20-AQ | 20 (40 μL) | 200 μL |  |
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| PAK5-20-DIG | 20 (40 μL) | 200 μL |  |
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| PAK5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PAK5
Gene Name: P21 (RAC1) Activated Kinase 5
Chromosome: CHR20: 9839041-9537389
Locus: 20p12.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PAK5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PAK5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping