PAK4 Break Apart FISH Probe
Empire Genomics’ PAK4 Break Apart FISH Probe is designed to flank the PAK4 gene and is typically used for detecting PAK4 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PAK4BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PAK4BA-20-AQOR | 20 (40 μL) | 200 μL |
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| PAK4BA-20-GOGR | 20 (40 μL) | 200 μL |
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| PAK4BA-20-GORE | 20 (40 μL) | 200 μL |
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| PAK4BA-20-GRGO | 20 (40 μL) | 200 μL |
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| PAK4BA-20-GROR | 20 (40 μL) | 200 μL |
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| PAK4BA-20-GRRE | 20 (40 μL) | 200 μL |
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| PAK4BA-20-REGO | 20 (40 μL) | 200 μL |
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| PAK4BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PAK4
Gene Name: P21 (RAC1) Activated Kinase 4
Chromosome: CHR19: 39616419-39670046
Locus: 19q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PAK4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PAK4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping