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PAK1 Break Apart FISH Probe

Empire Genomics’ PAK1 Break Apart FISH Probe is designed to flank the PAK1 gene and is typically used for detecting PAK1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
PAK1BA-20-GROR  (Standard Design) 20 (40 μL) 200 μL
PAK1BA-20-AQOR 20 (40 μL) 200 μL
PAK1BA-20-GOGR 20 (40 μL) 200 μL
PAK1BA-20-GORE 20 (40 μL) 200 μL
PAK1BA-20-GRGO 20 (40 μL) 200 μL
PAK1BA-20-GRRE 20 (40 μL) 200 μL
PAK1BA-20-ORGR 20 (40 μL) 200 μL
PAK1BA-20-REGO 20 (40 μL) 200 μL
PAK1BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

Gene Details

Gene Symbol: PAK1

Gene Name: P21 (RAC1) Activated Kinase 1

Chromosome: CHR11: 77033059-77185108

Locus: 11q13.5-q14.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure

Acral melanomas vary considerably in their molecular, histological, and clinical presentation. In this study, acral melanomas from dorsal, volar, and subungual-interdigital body sites were assessed using several tests, including FISH. Our TERT, CCND1, CDK4, AURKA, CDKN2A, PAK1, PTEN, NF1, and GAB2 probes were used to detect copy number variations in these genes. Genetic profiles were found to be tightly tied to UV exposure.
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Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure

Acral melanomas vary considerably in their molecular, histological, and clinical presentation. In this study, acral melanomas from dorsal, volar, and subungual-interdigital body sites were assessed using several tests, including FISH. Our TERT, CCND1, CDK4, AURKA, CDKN2A, PAK1, PTEN, NF1, and GAB2 probes were used to detect copy number variations in these genes. Genetic profiles were found to be tightly tied to UV exposure.
Read More

Product Details

Product: PAK1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PAK1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping