PACRG FISH Probe
The PACRG FISH probe is designed to hybridize to the PACRG gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PACRG-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
PACRG-20-RE | 20 (40 μL) | 200 μL | ||
PACRG-20-GO | 20 (40 μL) | 200 μL | ||
PACRG-20-GR | 20 (40 μL) | 200 μL | ||
PACRG-20-AQ | 20 (40 μL) | 200 μL | ||
PACRG-20-DIG | 20 (40 μL) | 200 μL | ||
PACRG-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PACRG
Gene Name: Parkin Coregulated
Chromosome: CHR6: 163148163-163736524
Locus: 6q26
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PACRG FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PACRG-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping