P4HB FISH Probe
The P4HB FISH probe is designed to hybridize to the P4HB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| P4HB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| P4HB-20-RE | 20 (40 μL) | 200 μL |  |
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| P4HB-20-GO | 20 (40 μL) | 200 μL |  |
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| P4HB-20-GR | 20 (40 μL) | 200 μL |  |
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| P4HB-20-AQ | 20 (40 μL) | 200 μL |  |
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| P4HB-20-DIG | 20 (40 μL) | 200 μL |  |
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| P4HB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: P4HB
Gene Name: Prolyl 4-hydroxylase Subunit Beta
Chromosome: CHR17: 79801033-79818544
Locus: 17q25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: P4HB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: P4HB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping