OTX2 Break Apart FISH Probe
Empire Genomics’ OTX2 Break Apart FISH Probe is designed to flank the OTX2 gene and is typically used for detecting OTX2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| OTX2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| OTX2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| OTX2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| OTX2BA-20-GORE | 20 (40 μL) | 200 μL |
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| OTX2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| OTX2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| OTX2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| OTX2BA-20-REGO | 20 (40 μL) | 200 μL |
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| OTX2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: OTX2
Gene Name: Orthodenticle Homeobox 2
Chromosome: CHR14: 57267424-57277184
Locus: 14q22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: OTX2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: OTX2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping