OTX2 FISH Probe
The OTX2 FISH probe is designed to hybridize to the OTX2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| OTX2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| OTX2-20-RE | 20 (40 μL) | 200 μL |  |
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| OTX2-20-GO | 20 (40 μL) | 200 μL |  |
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| OTX2-20-GR | 20 (40 μL) | 200 μL |  |
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| OTX2-20-AQ | 20 (40 μL) | 200 μL |  |
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| OTX2-20-DIG | 20 (40 μL) | 200 μL |  |
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| OTX2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: OTX2
Gene Name: Orthodenticle Homeobox 2
Chromosome: CHR14: 57267424-57277184
Locus: 14q22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: OTX2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: OTX2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping