ORC2 FISH Probe
The ORC2 FISH probe is designed to hybridize to the ORC2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ORC2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ORC2-20-RE | 20 (40 μL) | 200 μL |  |
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| ORC2-20-GO | 20 (40 μL) | 200 μL |  |
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| ORC2-20-GR | 20 (40 μL) | 200 μL |  |
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| ORC2-20-AQ | 20 (40 μL) | 200 μL |  |
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| ORC2-20-DIG | 20 (40 μL) | 200 μL |  |
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| ORC2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. [provided by RefSeq, Oct 2010]
Gene Details
Gene Symbol: ORC2
Gene Name: Origin Recognition Complex Subunit 2
Chromosome: CHR2: 201774893-201828424
Locus: 2q33.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ORC2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ORC2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping