OPTN FISH Probe
The OPTN FISH probe is designed to hybridize to the OPTN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| OPTN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| OPTN-20-RE | 20 (40 μL) | 200 μL |  |
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| OPTN-20-GO | 20 (40 μL) | 200 μL |  |
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| OPTN-20-GR | 20 (40 μL) | 200 μL |  |
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| OPTN-20-AQ | 20 (40 μL) | 200 μL |  |
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| OPTN-20-DIG | 20 (40 μL) | 200 μL |  |
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| OPTN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: OPTN
Gene Name: Optineurin
Chromosome: CHR10: 13142081-13180276
Locus: 10p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: OPTN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: OPTN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping