OPRK1 FISH Probe
The OPRK1 FISH probe is designed to hybridize to the OPRK1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| OPRK1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| OPRK1-20-RE | 20 (40 μL) | 200 μL |  |
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| OPRK1-20-GO | 20 (40 μL) | 200 μL |  |
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| OPRK1-20-GR | 20 (40 μL) | 200 μL |  |
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| OPRK1-20-AQ | 20 (40 μL) | 200 μL |  |
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| OPRK1-20-DIG | 20 (40 μL) | 200 μL |  |
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| OPRK1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
Gene Details
Gene Symbol: OPRK1
Gene Name: Opioid Receptor Kappa 1
Chromosome: CHR8: 54138275-54164194
Locus: 8q11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: OPRK1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: OPRK1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping