OB FISH Probe
The OB FISH probe is designed to hybridize to the OB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LEP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LEP-20-RE | 20 (40 μL) | 200 μL |  |
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| LEP-20-GO | 20 (40 μL) | 200 μL |  |
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| LEP-20-GR | 20 (40 μL) | 200 μL |  |
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| LEP-20-AQ | 20 (40 μL) | 200 μL |  |
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| LEP-20-DIG | 20 (40 μL) | 200 μL |  |
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| LEP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the brain, which activates downstream signaling pathways that inhibit feeding and promote energy expenditure. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis, reproduction, bone formation and wound healing. Mutations in this gene and its regulatory regions cause severe obesity and morbid obesity with hypogonadism in human patients. A mutation in this gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: LEP
Gene Name: Leptin
Chromosome: CHR7: 127881330-127897682
Locus: 7q32.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: OB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LEP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping