NUS1 FISH Probe
The NUS1 FISH probe is designed to hybridize to the NUS1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NUS1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NUS1-20-RE | 20 (40 μL) | 200 μL |  |
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| NUS1-20-GO | 20 (40 μL) | 200 μL |  |
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| NUS1-20-GR | 20 (40 μL) | 200 μL |  |
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| NUS1-20-AQ | 20 (40 μL) | 200 μL |  |
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| NUS1-20-DIG | 20 (40 μL) | 200 μL |  |
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| NUS1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a type I single transmembrane domain receptor, which is a subunit of cis-prenyltransferase, and serves as a specific receptor for the neural and cardiovascular regulator Nogo-B. The encoded protein is essential for dolichol synthesis and protein glycosylation. This gene is highly expressed in non-small cell lung carcinomas as well as estrogen receptor-alpha positive breast cancer cells where it promotes epithelial mesenchymal transition. This gene is associated with the poor prognosis of human hepatocellular carcinoma patients. Naturally occurring mutations in this gene cause a congenital disorder of glycosylation and are associated with epilepsy. A knockout of the orthologous gene in mice causes embryonic lethality before day 6.5. Pseudogenes of this gene have been defined on chromosomes 13 and X. [provided by RefSeq, May 2017]
Gene Details
Gene Symbol: NUS1
Gene Name: NUS1 Dehydrodolichyl Diphosphate Synthase Subunit
Chromosome: CHR6: 117996616-118031886
Locus: 6q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NUS1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NUS1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping